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In 2012, scientists described a new tool for editing DNA that would transform biology. Called CRISPR-Cas9, it was adapted from a defense system that bacteria use against viruses.
The system works like molecular scissors guided by a GPS. A short strand of RNA guides the Cas9 protein to a precise location in the genome, where it cuts the DNA. The cell then repairs the cut, and scientists can use that moment to disable a gene or insert a new sequence.
CRISPR is faster, cheaper and more precise than earlier gene-editing methods. Researchers are using it to develop treatments for inherited diseases such as sickle cell disease, and in 2023 regulators in the U.K. and the U.S. approved the first CRISPR-based therapy for that condition.
The technology also raises ethical questions, especially about editing human embryos, where changes could be passed to future generations. Many scientists have called for strict limits on such uses.
| Claim or central idea | |
|---|---|
| Reason / evidence 1 | |
| Reason / evidence 2 | |
| Counterclaim (if any) | |
| Is the evidence relevant and sufficient? Why? |
Worksheets › Grade 10 English › Integration of Knowledge & Ideas › Integration of Knowledge & Ideas
Free Grade 10 English worksheet (Common Core RI.9-10.8): trace and evaluate the argument and claims in "CRISPR: Editing the Code of Life", judging whether the evidence is relevant and sufficient. Skill: Compare texts and evaluate arguments. Level: Grade 10 — also suits Year 11 (UK).
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It is designed for Grade 10 (ages 15–16), but use it with any child who is ready.
Compare texts and evaluate arguments.
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Integration of Knowledge & Ideas: Compare Texts: The Road Not Taken & The Gettysburg Address (Grade 10) · Integration of Knowledge & Ideas: Compare Texts: Afterglow & Should the Voting Age Be Lowered to 16? (Grade 10) · Integration of Knowledge & Ideas: Evaluate an Argument: The Gettysburg Address (Grade 10) · Integration of Knowledge & Ideas: Compare Texts: Translation & The Dust Bowl (Grade 10)
All 5 integration of knowledge & ideas sheets → · Grade 10 English: all 10 skills → · All Common Core grades
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